One significant difference is that for adults, the maximum dose of articaine is now determined strictly by the patient's weight.
Maximum Dose of Anesthetics in Adult Patients
|
Anesthetic |
Maximum Dose (mg/kg) |
Maximum Allowable Dose |
Limiting Agent |
|
Articaine 4% |
7.0 mg |
Weight-dependent |
Anesthetic |
|
Lidocaine 2% + 1:100,000 epinephrine |
7.0 mg |
500 mg |
Vasoconstrictor |
|
Lidocaine 2% + 1:50,000 epinephrine |
7.0 mg |
500 mg |
Vasoconstrictor |
|
Mepivacaine 3% (with or without vasoconstrictor) |
6.6 mg |
400 mg |
Anesthetic |
Limiting Agent: The specific component that determines the maximum dose limit. Example: Once the maximum dose of the vasoconstrictor in Lidocaine is reached, no additional doses of the preparation should be administered, even if the maximum dose of the anesthetic agent itself has not been reached.
Maximum Dose of Anesthetics in Pediatric Patients
|
Anesthetic |
Maximum Dose (mg/kg) |
Maximum Allowable Dose |
|
Articaine 4% |
7.0 mg |
300 mg |
|
Mepivacaine 2% / 3% |
4.4 mg |
300 mg |
|
Lidocaine 2% |
4.4 mg |
500 mg |
Note: The information in this article and the accompanying tables is provided for informational purposes only. Some of these anesthetic dosages differ from those approved EU legislation and others, rendering the direct clinical application of this specific data inappropriate in those regions or in some clinical situations.
